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PDF hosted at the Radboud Repository of the Radboud University
PDF hosted at the Radboud Repository of the Radboud University

... were then combined with any of the following: substance abuse, substance dependence, substance use disorder and substance withdrawal. In addition, we reviewed all the papers with these same keywords in the July to December 1991 issues of 18 psychiatric journals (published in English), because at the ...
- University of Mississippi
- University of Mississippi

... become limp and unexpectedly drop to the ground. These seizures are also referred to as drop attacks and often result in injury (“Types of Seizures”, 2016). Unlike generalized seizures, in focal/partial seizures consciousness is not lost and the region of the brain affected is limited to a particul ...
Cilansetron - Open Access Journals
Cilansetron - Open Access Journals

... (Zelnorm™, Novartis Pharmaceuticals Corp., NJ, USA), a partial agonist, is useful in women with the constipation-predominant form of IBS. Alosetron (Lotronex™, GlaxoSmithKline plc, London, UK), a 5-HT3 receptor antagonist, is effective in women with severe diarrheapredominant IBS; however, its use i ...
Evaluating Drugs Used To Treat: Constipation
Evaluating Drugs Used To Treat: Constipation

... Age – Constipation is more common in older people. This is in part because slowing of the bowel functions is a natural part of the aging process and because the elderly are often on medications that slow the gastrointestinal tract. Changes in routine – Many people become constipated while traveling, ...
Bergamottin and “The Grapefruit Juice Effect”
Bergamottin and “The Grapefruit Juice Effect”

... furan ring is activated to a reactive intermediate which covalently modifies a critical part in the active site of the enzyme3. Also, studies were done that proved that a metabolite of bergamottin was covalently bound to the CYP450 3A4 apoprotein during inactivation by using SDS PAGE and the masses ...
Circulatory Disorders
Circulatory Disorders

... thrombophlebitis - Both inflammation and clots are present Some thrombus can be superficial but it’s the DVT that’s a concern  embolism to lungs. ...
Responsibility for Addiction
Responsibility for Addiction

... motivational, emotional and memory centers that are co-located within the limbic system. These interconnected regions allow the organism not only to experience the pleasure of rewards, but also to learn the signals for them and to respond in an anticipatory manner. Repeated pairing of a person (drug ...
Synergistic anti-inflammatory Activity of Lawsonia Inermis linn. and
Synergistic anti-inflammatory Activity of Lawsonia Inermis linn. and

... Nonsteroidal and steroidal drugs are generally used to treat inflammation. However, these drugs have side-effects like nausea, vomiting, etc. This lead to search for new anti-inflammatory agents from natural sources, which would be effective and safe. Many plant extracts show a synergistic effect wi ...
Opioid Receptors and Legal Highs - The Salvia divinorum Research
Opioid Receptors and Legal Highs - The Salvia divinorum Research

... Hallucinations occur rapidly after administration and are typically very vivid (27). Salvia divinorum produces synesthesia as its characteristic psychotropic effect; many users report a confusion of the senses, like hearing colors or smelling sounds (27). Hallucinogenic effects are typically brief, ...
Ciprofloxacin sensitizes hormone-refractory prostate cancer cell
Ciprofloxacin sensitizes hormone-refractory prostate cancer cell

... within the 100-lM range (Tables 1 and 2). Growth inhibition between 0 and almost 100%, relatively to untreated control cells, were easily achieved with the selected concentration range tested (Fig. 1). The most significant differences in drug IC50 values between the two cell lines were verified for ...
No Slide Title
No Slide Title

TOPICALLY APPLIED NSAIDs IN THE TREATMENT OF PAIN
TOPICALLY APPLIED NSAIDs IN THE TREATMENT OF PAIN

... most NSAIDs have lost their patents which makes the development of topical preparations unprofitable for drug companies. Nevertheless, topical NSAIDs are widely available and are prescribed extensively in other countries. Topical NSAIDs have four major advantages: 1) higher concentrations of NSAIDs ...
Antibiotic Resistance. Because of overuse and misuse, some
Antibiotic Resistance. Because of overuse and misuse, some

... an evolutionary inevitability, even where antimicrobials are used properly and sparingly. All microbes have the potential to mutate and render drugs ineffective. Once a few have mutated, they spread when antibiotics wipe out the susceptible bacteria, leaving a niche for the resistant ones to occupy. ...
Pharmacotherapy In Cardiopulmonary Resuscitation (CPR)
Pharmacotherapy In Cardiopulmonary Resuscitation (CPR)

... indeterminate (5). It is not established whether a second dose of vasopressin is required or not (1). Since vasopressin is one of the most important endogenously released stress hormones during shock, vasopressin and its analogs may also be useful to treat septic and catecholamine-resistant shock an ...
LWW PPT Slide Template Master - Medical College Admission Test
LWW PPT Slide Template Master - Medical College Admission Test

... person has a chronic or compulsive need for a drug regardless of its adverse effects; dependence may be psychological or physical ...
LABEL Infopest Verified
LABEL Infopest Verified

... involved in inflammation. Inhibition of COX-1 is thought to be associated with gastrointestinal and renal toxicity while inhibition of COX-2 provides anti-inflammatory activity. The specificity of a particular NSAID for either COX-2 or COX-1 may vary from species to species. In an in vitro study usi ...
Diterpenes-A Review on Therapeutic uses with special emphasis on
Diterpenes-A Review on Therapeutic uses with special emphasis on

... product extracts maintaining their originally present important ingredients is getting popular due to toxicities encountered in drug discovery. Due to drying up of pipeline from big pharma industries, CAM is a sought after source for new leads in drug discovery and contimues to challenge development ...
Guideline on Fixed Combinations - EMA
Guideline on Fixed Combinations - EMA

... and effective for a significant population subgroup and the benefit/risk assessment of the fixed combination is equal or exceeds the one of each of its substances taken alone. The multilevel factorial design may be used but other confirmatory strategies exist to prove that the combination is superio ...
Product Information - Therapeutic Goods Administration
Product Information - Therapeutic Goods Administration

... muscle cramps, confusional state, delirium, hallucinations, hyperthermia, psychosis, vomiting and sweating. Such manifestations of withdrawal, especially the more serious ones are more common in patients who have received excessive doses over a prolonged period. However, withdrawal symptoms have bee ...
The Ups and Downs of Cognitive Enhancers
The Ups and Downs of Cognitive Enhancers

... chemicals with the potential to enhance cognitive function that are less well represented in the scientific literature. For an overview on these types of substances, it is best to look at the relatively newlyestablished field of “nootropics.” Dwivedi et al. describes nootropics as: “drugs, supplemen ...
7 Alma Jarkas
7 Alma Jarkas

...  You can notice that they end by “” Dronate “”.  Why there are a lot of these drugs ?!| because it’s a successful trade and some can be given daily , weekly ,monthly ,,,etc . remember the compliance !  They retard formation and dissolution of hydroxyapatite crystals within and outside the skeleta ...
NIDA Research Report - Heroin
NIDA Research Report - Heroin

... a wider variety of treatment settings than the currently available medications. Several other medications with potential for treating heroin overdose or addiction are currently under investigation by NIDA. In addition to methadone and buprenorphine, other drugs aimed at reducing the severity of the ...
Product Monograph - Paladin Labs Inc.
Product Monograph - Paladin Labs Inc.

Opioids - David Kan, MD
Opioids - David Kan, MD

... Efficacy and Effectiveness often diverge in treatment of opiate addiction Methadone Maintenance is the Gold Standard for good outcomes Buprenorphine has a better safety profile, and it may be prescribed from ...
Sedation Controlled
Sedation Controlled

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Psychopharmacology



Psychopharmacology (from Greek ψῡχή, psȳkhē, ""breath, life, soul""; φάρμακον, pharmakon, ""drug""; and -λογία, -logia) is the scientific study of the effects drugs have on mood, sensation, thinking, and behavior. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior.The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain.Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their receptors is referred to as ""drug action"", and the widespread changes in physiological or psychological function is referred to as ""drug effect"". These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical synthesis in the laboratory.
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