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Profile Documents Logout
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The Proportional Venn Diagram of Obstructive Lung Disease*
The Proportional Venn Diagram of Obstructive Lung Disease*

... consensus definitions of asthma3 and COPD, including chronic bronchitis and emphysema,4 are available, but the diagnosis of OLDs is a medical challenge for respiratory specialists and primary care physicians, even with the availability of spirometry or a patient history of tobacco use.5 This differe ...
Orally exhaled nitric oxide levels are related to the degree... blood eosinophilia in atopic children with mild-intermittent
Orally exhaled nitric oxide levels are related to the degree... blood eosinophilia in atopic children with mild-intermittent

... increased bulk of airway smooth muscle ("airway remodelling"). Because of these observations, various clinical practice guidelines recommend maintenance treatment with anti-inflammatory drugs for all patients with asthma, except for those with mild-intermittent disease [7, 8]. However, recent report ...
A Is difficult asthma still clinically meaningful? EDITORIAL
A Is difficult asthma still clinically meaningful? EDITORIAL

... and reversibility of symptoms) and functional. There have been several studies on the sensitivity and specificity of the functional signs of asthma and their predictive values are clearly insufficient. Those maintained in the international recommendations are cough, dyspnoea, wheezing, chest tightne ...
Breathe Easy How to Approach Unresponsive Asthma
Breathe Easy How to Approach Unresponsive Asthma

... Environmental and other external factors Exposure to many environmental antigens can result in poor asthma control. Continuing exposure to domestic antigens, such as cockroach antigen and fur-bearing pets, increases airway inflammation. Amongst the nonallergic exposures, tobacco smoke is the most im ...
AIMAR survey on complex forms of bronchial asthma and COPD
AIMAR survey on complex forms of bronchial asthma and COPD

... survey was administered were basically three (pneumologists, allergologists, and internal medicine specialists) with extension to general practitioners (GPs). The survey consisted of 18 multiple-choice questions completed by means of a web-based electronic form published in internet - time required ...


... date was associated with a slightly increased OR; this probability losing significance when the adjusted OR was computed. This finding could suggest that inhaled corticosteroids would not protect patients against the occurrence of exacerbations, a result which is in contrast to previous outcomes dem ...
SERIES 0CONTROVERSIES IN OCCUPATIONAL ASTHMA0 Number 2 in this Series
SERIES 0CONTROVERSIES IN OCCUPATIONAL ASTHMA0 Number 2 in this Series

... while at work or when exposed to agents usually present at the workplace. Finally, another crucial issue is the practicality of applying these different tools in varying circumstances. In many countries, the existing workers9 compensation systems are not sufficient to facilitate the satisfactory man ...
How much is too much? The treatment of mild asthma EDITORIAL
How much is too much? The treatment of mild asthma EDITORIAL

... BDP and salbutamol was significantly better in reducing asthma exacerbations than either arm that contained regular salbutamol use raises a number of interesting issues. The first of these is that any treatment option that contains regular salbutamol treatment should be avoided in mild asthma. Secon ...
Diagnosis of respiratory diseases in primary care
Diagnosis of respiratory diseases in primary care

... their first presentation of a chronic disease such as asthma or diabetes. The challenge for primary care clinicians is to determine whether or not the new symptoms represent a life-threatening emergency, a short-term problem likely to resolve spontaneously, or an evolving chronic health condition. Un ...
Environmental Management - American Lung Association
Environmental Management - American Lung Association

... of randomized controlled trials (RCT) • Evidence B – Limited body of data – some RCTs • Evidence C – Non-randomized trials and observational studies • Evidence D – Panel consensus judgment (for when guidance seems valuable but lacks literature backing) ...
Document
Document

... chemicals the body releases to combat certain stimuli, called allergens. • Allergic reactions occur most often in response to five categories of stimuli: insect bites and stings, medications, food, plants, and chemicals. ...
PPT - MSU Institute for Health Policy
PPT - MSU Institute for Health Policy

... Informed Consent: “I have discussed the likelihood of major risks or complications from this procedure (if applicable) but not limited to…” ...
Case-control study of severe life threatening asthma (SLTA)
Case-control study of severe life threatening asthma (SLTA)

... previously documented in the UK and Australia.11 16 17 Living in a rural area may limit access to specialised care that, in turn, could lead to suboptimal asthma management, particularly in severe asthma. Our data also confirmed an association between SLTA and low economic standing as reflected by a ...
A Rationale
A Rationale

... chemicals the body releases to combat certain stimuli, called allergens. • Allergic reactions occur most often in response to five categories of stimuli: insect bites and stings, medications, food, plants, and chemicals. ...
Diagnosing Asthma - Seattle Children`s Hospital
Diagnosing Asthma - Seattle Children`s Hospital

... Dexamethasone is approximately 5 times more potent than prednisone, so the dose is 0.40.6 mg/kg/day. Dexamethasone is longer acting than prednisone, so it can be given once daily, while prednisone is usually administered twice daily. Dexamethasone tablets do not taste as bad as prednisone tablets, s ...
Rhitinis and Asthma: One Airway, One Disease
Rhitinis and Asthma: One Airway, One Disease

... often present concurrently. The high prevalence of these diseases is associated with high morbidity and elevated health costs. Both diseases have a number of characteristics in common, but they also differ substantially in certain aspects. In 2001, the Allergic Rhinitis and Its Impact on Asthma (ARI ...
Slide 1
Slide 1

... Patient need to be seen every 3-6 months Or earlier if patient deteriorate ...
The Role of Sinus Disease in Asthma
The Role of Sinus Disease in Asthma

... In a study comparing patients with mild-to-moderate asthma with corticosteroid dependent asthmatic patients,[34] about 70% of all participants reported symptoms of rhinosinusitis. The total symptom score, however, was significantly higher in patients with severe steroid dependent asthma than in thos ...
Same role and same treatment for airway eosinophilia EDITORIAL
Same role and same treatment for airway eosinophilia EDITORIAL

... second, the reduction of severe exacerbation represents an important achievement of the treatment strategy; in fact, exacerbations contribute to the progression of the disease, increase the risk of mortality and lead to enormous economic costs. Moreover, these results were obtained with average dail ...
Asthma Management In Educational Settings
Asthma Management In Educational Settings

... going to the office or nurse’s office Property of The Amerrican Lung Association of Washington ...
Ibuprofen-induced bronchospasm
Ibuprofen-induced bronchospasm

... has increased dramatically. Thousands of children with asthma take ibuprofen each year, often during acute illnesses, including upper respiratory tract infections. It is possible that ibuprofen may exacerbate asthma in some of these children, but the risk is not yet known and few studies have evalua ...
Asthma
Asthma

... Airflow obstruction = FEV1/FVC ratio < 70% Severity then categorized by reduction in FEV1 Mild obstruction = 65-80%  Moderate obstruction = 50-65%  Severe obstruction = <50%  Very Severe obstruction = < 35% ...
Asthma Control in Hospital Tengku Ampuan Afzan, Kuantan, Malaysia
Asthma Control in Hospital Tengku Ampuan Afzan, Kuantan, Malaysia

... Fax: +609-5171897 Tel: +609-5706000 ...
available should be possible. However, believe there  is
available should be possible. However, believe there is

... These episodes tend to decrease with age both in number and severity. On the other hand, chronic symptoms characterized by cough and wheeze particularly at night or after exercise, unrelated to viral infections, tend to increase with age from about Lhe age of 3 years, although they can begin earlier ...
37 Wheezing and Asthma
37 Wheezing and Asthma

... hypoxia . Most asthmatics complain of greater difficulty during inspiration than expiration, due to the uncomfortable work of breathing necessary to ventilate hyperinflated, abnormally stiff, or noncompliant lungs . Several hypotheses have been proposed to explain the pathogenesis of bronchoconstric ...
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Omalizumab

Omalizumab (trade name Xolair, Roche/Genentech and Novartis) is a humanized antibody originally designed to reduce sensitivity to inhaled or ingested allergens, especially in the control of moderate to severe allergic asthma, which does not respond to high doses of corticosteroids. It has been approved for treating adult and adolescent patients 12 years and older with severe or moderate to severe allergic asthma in more than 90 countries, since its first of such approval in 2002 in Australia. Omalizumab was approved in March 2014 in the European Union and the U.S.A. and in about 10 other countries for treating patients 12 years and above with chronic spontaneous urticaria (CSU) (also referred to as chronic idiopathic urticaria or CIU), which cannot be treated with H1-antihistamines. CSU is not an allergic disease. Presently, the drug is being actively studied in clinical trials for various allergic diseases and some non-allergic diseases, especially skin diseases.Omalizumab is a recombinant DNA-derived humanized IgG1k monoclonal antibody that specifically binds to free human immunoglobulin E (IgE) in the blood and interstitial fluid and to membrane-bound form of IgE (mIgE) on the surface of mIgE-expressing B lymphocytes. Unlike an ordinary anti-IgE antibody, it does not bind to IgE that is already bound by the high affinity IgE receptor (FcεRI) on the surface of mast cells, basophils, and antigen-presenting dendritic cells.IgE is commonly involved in type I hypersensitivity, which manifests the most prevalent allergic diseases. It has been estimated that as high as 20 to 40% of the populations who live a western lifestyle in economically advanced countries are affected by allergy and seek medical help. In the U.S., 8% of adults and 10% of children have asthma. Allergy occurs more frequently in individuals with higher serum IgE levels, though some allergic individuals have very low serum IgE, and some people with very high IgE have no allergic problems.
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