Treatment of plague: promising alternatives to antibiotics
... Y. pestis is primarily a rodent pathogen, and is usually transmitted to another mammalian host by fleas, following the death of the rodent. After being introduced into the host, the bacterium is initially susceptible to phagocytosis and killing by neutrophils (Cavanaugh & Randall, 1959) and CD11c+ c ...
... Y. pestis is primarily a rodent pathogen, and is usually transmitted to another mammalian host by fleas, following the death of the rodent. After being introduced into the host, the bacterium is initially susceptible to phagocytosis and killing by neutrophils (Cavanaugh & Randall, 1959) and CD11c+ c ...
Backcalculation of the disease-age specific frequency of secondary
... as disease-age specific infectiousness. Both the numbers of those who are considered as ...
... as disease-age specific infectiousness. Both the numbers of those who are considered as ...
Bubonic plague: a metapopulation model of a zoonosis
... In a previous paper (Keeling & Gilligan 2000), we introduced a stochastic metapopulation model for bubonic plague. Here we consider the full deterministic dynamics and stochastic behaviour in more detail. In particular, we concentrate on the rat dynamics at the local spatial scale, showing that the ...
... In a previous paper (Keeling & Gilligan 2000), we introduced a stochastic metapopulation model for bubonic plague. Here we consider the full deterministic dynamics and stochastic behaviour in more detail. In particular, we concentrate on the rat dynamics at the local spatial scale, showing that the ...
The Genome of the Black Death: Full Genome analysis of ancient
... The Black Death • The Black Death was one of the most devastating epidemics in human history • It lasted only 5 years (1347-1351) and 25-50 million Europeans died of the epidemic • likely originated in China • Suspected disease bubonic plague caused by Yersinia pestis gram negative bacteria ...
... The Black Death • The Black Death was one of the most devastating epidemics in human history • It lasted only 5 years (1347-1351) and 25-50 million Europeans died of the epidemic • likely originated in China • Suspected disease bubonic plague caused by Yersinia pestis gram negative bacteria ...
What is plague? - The University of Sydney
... very quickly at body temperature and produces a capsule that protects it from the body’s defences. It then multiplies and releases toxins into the bloodstream that cause swelling nodes, leading to septicaemia and death. The high bacterial content of the tissues at death means that humans who handle ...
... very quickly at body temperature and produces a capsule that protects it from the body’s defences. It then multiplies and releases toxins into the bloodstream that cause swelling nodes, leading to septicaemia and death. The high bacterial content of the tissues at death means that humans who handle ...
Biological Threats - Georgia Poison Center
... BT attack is inhalational disease; cutaneous disease is also possible • Early in the course of illness, inhalational anthrax is not easily distinguished from an influenza-like illness due to other causes • Antibiotic prophylaxis can be used to prevent development of disease in infected persons • Ant ...
... BT attack is inhalational disease; cutaneous disease is also possible • Early in the course of illness, inhalational anthrax is not easily distinguished from an influenza-like illness due to other causes • Antibiotic prophylaxis can be used to prevent development of disease in infected persons • Ant ...
Terrorism 101
... floors. It was released as terrorists punctured the containers with umbrellas before leaving the trains. •.On April 19th, 1995 repeat attack in subway which the same terrorist group killed seven and injured more than 200 people. ...
... floors. It was released as terrorists punctured the containers with umbrellas before leaving the trains. •.On April 19th, 1995 repeat attack in subway which the same terrorist group killed seven and injured more than 200 people. ...
Zoonosis Update - American Veterinary Medical Association
... 15th centuries.1 Far from being a historic medical curiosity, this zoonotic disease continues to be a threat to the health of humans and animals in the western United States and throughout the world, including Eurasia, Africa, and North and South America.2 In addition to rodents, a number of mammali ...
... 15th centuries.1 Far from being a historic medical curiosity, this zoonotic disease continues to be a threat to the health of humans and animals in the western United States and throughout the world, including Eurasia, Africa, and North and South America.2 In addition to rodents, a number of mammali ...
A History of the Human Plague in Iran
... Ghazvin and spread to other cities, including Abhar, Tarom, Khalkhal, Zanjan, Azarbaijan, and Gilan. In Ghazvin 20,000 people died. After the collapse of the Safavid Dynasty and Iran’s occupation by the Afghan invaders, another plague outbreak occurred in Gilan Province in 1727 with a high mortality ...
... Ghazvin and spread to other cities, including Abhar, Tarom, Khalkhal, Zanjan, Azarbaijan, and Gilan. In Ghazvin 20,000 people died. After the collapse of the Safavid Dynasty and Iran’s occupation by the Afghan invaders, another plague outbreak occurred in Gilan Province in 1727 with a high mortality ...
Pneumonic Plague
... health department of their concern for Y. pestis, and the isolated organism was transported to their laboratory for definitive identification. In the meantime, with a presumptive diagnosis of pneumonic plague, gentamicin, doxycycline, and ciprofloxacin were added to the patient’s antibiotic regimen; ...
... health department of their concern for Y. pestis, and the isolated organism was transported to their laboratory for definitive identification. In the meantime, with a presumptive diagnosis of pneumonic plague, gentamicin, doxycycline, and ciprofloxacin were added to the patient’s antibiotic regimen; ...
Black Death Spring 2017 syllabus - Amigos de la Historia Veterinaria
... health interventions, and then antibiotics helped us gained control over the major global infectious diseases, epidemics and pandemics were a fact of life. The most severe pandemic in human history was the Black Death, which struck Afroeurasia towards the end of the Middle Ages. Although total (abso ...
... health interventions, and then antibiotics helped us gained control over the major global infectious diseases, epidemics and pandemics were a fact of life. The most severe pandemic in human history was the Black Death, which struck Afroeurasia towards the end of the Middle Ages. Although total (abso ...
Plague pdf, 2.80Mb - WHO South
... Major epidemics are most likely to occur when rats living in close association with humans come in contact with the wild rodent reservoirs of plague. A large population of these rats, and infestation with vector fleas, aids the spread. Usually these conditions are found in poverty-stricken areas wit ...
... Major epidemics are most likely to occur when rats living in close association with humans come in contact with the wild rodent reservoirs of plague. A large population of these rats, and infestation with vector fleas, aids the spread. Usually these conditions are found in poverty-stricken areas wit ...
The Black Death of 1347-1351
... that 34 million died in Europe over the next four years, and plague epidemics hit Asia and the Middle East at the same time period, killing more people there and making the plague a multi-regional pandemic; it is estimated that up to two-thirds of China’s population may have died—approximately 25 mi ...
... that 34 million died in Europe over the next four years, and plague epidemics hit Asia and the Middle East at the same time period, killing more people there and making the plague a multi-regional pandemic; it is estimated that up to two-thirds of China’s population may have died—approximately 25 mi ...
Plague - Forest Hills High School
... Primary: occurs when a flea inserts y. pestis directly into the bloodstream Secondary: occurs as a severe development from bubonic or pneumonic (when y pestis migrates to bloodstream) ...
... Primary: occurs when a flea inserts y. pestis directly into the bloodstream Secondary: occurs as a severe development from bubonic or pneumonic (when y pestis migrates to bloodstream) ...
pdp plague facts - Prairie Dog Pals
... In the wild, prairie dogs are the victims of only one disease, plague. Plague was introduced to the west by settlers near the turn of the century and, “...we gave it to the prairie dogs.”1 It was first discovered in New Mexico in 19382. This non-native disease is spread by fleas and is carried into ...
... In the wild, prairie dogs are the victims of only one disease, plague. Plague was introduced to the west by settlers near the turn of the century and, “...we gave it to the prairie dogs.”1 It was first discovered in New Mexico in 19382. This non-native disease is spread by fleas and is carried into ...
Biological Warfare Agents
... Mng: immediate notification of public health; standard barrier isolation, no need for air filter masks; no direct contact with skin lesions; surface decontamination with bleach and water; urgent Abx; assume resistance to penicillin and tetracycline if terrorist attack; use cipro 400mg IV BD + rifamp ...
... Mng: immediate notification of public health; standard barrier isolation, no need for air filter masks; no direct contact with skin lesions; surface decontamination with bleach and water; urgent Abx; assume resistance to penicillin and tetracycline if terrorist attack; use cipro 400mg IV BD + rifamp ...
Plague into the 21st Century
... A sick camel in Saudi Arabia in 1994 was the source of 5 cases, with 2 deaths; 4 persons who ate raw camel liver developed pharyngitis, and 1 person who had butchered the camel developed an axillary bubo [17]. Primary inhalational lung infection is a rare form of transmission but can propagate perso ...
... A sick camel in Saudi Arabia in 1994 was the source of 5 cases, with 2 deaths; 4 persons who ate raw camel liver developed pharyngitis, and 1 person who had butchered the camel developed an axillary bubo [17]. Primary inhalational lung infection is a rare form of transmission but can propagate perso ...
Biological Terrorist Agents Part 1
... which may result in a high death rate. Fleas that have lost their usual hosts pursue alternative sources of blood. When this happens, the risk to humans and other animals is increased. Epidemics of plague in humans commonly involve house rats and their fleas. Animals prone to be carriers in the Unit ...
... which may result in a high death rate. Fleas that have lost their usual hosts pursue alternative sources of blood. When this happens, the risk to humans and other animals is increased. Epidemics of plague in humans commonly involve house rats and their fleas. Animals prone to be carriers in the Unit ...
Population Biology of Infectious Diseases
... 3. An epidemic will usually only spread in one metro area. 4. Diffusion constant has no effect on whether the epidemic occurs but it has effect on spread speed if the epidemic occurs. ...
... 3. An epidemic will usually only spread in one metro area. 4. Diffusion constant has no effect on whether the epidemic occurs but it has effect on spread speed if the epidemic occurs. ...
plague - sfcdcp
... care delivery system can effectively manage the number of patients, IV antibiotics should be administered to all patients for 10 days (Table 1). Oral antibiotics can be substituted once the patient’s condition improves. In a mass casualty setting where the medical care delivery system is not able to ...
... care delivery system can effectively manage the number of patients, IV antibiotics should be administered to all patients for 10 days (Table 1). Oral antibiotics can be substituted once the patient’s condition improves. In a mass casualty setting where the medical care delivery system is not able to ...
Bubonic Plague Reading Material to Accompany Activity by Elizabeth Buda
... understaffed, since most of the world's governments have grown complacent about the risk of a fourth plague pandemic. Their complacency is far from warranted. In the first place, rodenticides and insecticides used to control rat and flea populations in urban areas are no longer as effective as they ...
... understaffed, since most of the world's governments have grown complacent about the risk of a fourth plague pandemic. Their complacency is far from warranted. In the first place, rodenticides and insecticides used to control rat and flea populations in urban areas are no longer as effective as they ...
Appendix A: Disease-Specific Chapters
... in the 1930s and 1990s.3 Transmission of plague to humans in Canada is extremely rare. The last reported human case occurred in 1939.4 The last laboratory confirmed cases of plague in Canadian wildlife included two bushy-tailed woodrats in the Lillooet area of British Columbia in 1988, and a black-t ...
... in the 1930s and 1990s.3 Transmission of plague to humans in Canada is extremely rare. The last reported human case occurred in 1939.4 The last laboratory confirmed cases of plague in Canadian wildlife included two bushy-tailed woodrats in the Lillooet area of British Columbia in 1988, and a black-t ...
Plague
... bacterium persists in 'foci' of infected rodents1'2'10. The observation that distinct foci of infection occur at sites throughout the world indicates that the bacterium can persist for long periods in some relatively resistant (enzootic) animal hosts and their fleas1*2'10. For this reason it would b ...
... bacterium persists in 'foci' of infected rodents1'2'10. The observation that distinct foci of infection occur at sites throughout the world indicates that the bacterium can persist for long periods in some relatively resistant (enzootic) animal hosts and their fleas1*2'10. For this reason it would b ...
Plague (disease)
Plague is an infectious disease that is caused by the bacteria Yersinia pestis. Depending on lung infection, or sanitary conditions, plague can be spread in the air, by direct contact, or very rarely by contaminated undercooked food. The symptoms of plague depend on the concentrated areas of infection in each person: bubonic plague in lymph nodes, septicemic plague in blood vessels, pneumonic plague in lungs. It is treatable if detected early. Plague is still relatively common in some remote parts of the world.Until June 2007, plague was one of the three epidemic diseases specifically reportable to the World Health Organization (cholera and yellow fever the other two). The bacteria is named after the French-Swiss bacteriologist Alexandre Yersin.