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Transcript
KS4/KS5 activity New biotechnology: Growing a liver in a laboratory Procedure How this works What this new technology could replace What are the advantages of this new technology over the old? Are there any limitations/disadvantages of using this technology? Creating a liver in a lab Stem cells are used to grow a new liver on the connective tissue and blood vessel scaffold of an old liver. Organ transplants • The stem cells would be from the patient so the organ would not be rejected. • Donor livers that are too damaged to be used for traditional transplants could be used for the scaffold. The stem cells might come from embryos which raises ethical questions. © Snapshot Science, 2010 KS5 activity New biotechnology: Creating plastic antibodies Procedure How this works What this new technology could replace What are the advantages of this new technology over the old? Are there any limitations/disadvantages of using this technology? Creating plastic antibodies Polymers would be used to create a ‘molecular imprint’ around the antigen of interest - a bit like making a plaster cast of a footprint. Monoclonal antibodies produced using hybridoma cells • No need for using cells or animals to create the antibodies so less ethical dilemmas. • Antibodies can be ‘tailor made’ to lock onto a massive range of different antigens like pathogens and proteins that cause allergic reactions. • The plastic antibodies cannot communicate with other cells so are unable to set up an immune response (so could not be used in vaccinations for example). • Could the liver cope with removing the antibodies from the body? © Snapshot Science, 2010