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毛首线虫 Trichuris sp. 主讲: 刘园 组员:刘园 胡伟高 江保祯 皮瀛江 毛首线虫 Trichuris sp. Whipworm(鞭虫),a kind of common nematodes(线虫) in pig and human,the adults of whipworm live in colon of pig, cause trichuriasis(鞭虫病)。 一、形 态(Morphology) 1.成虫(adult) Like whip, the front 3/5 is slender,the end 2/5 is bulky. The females are big,the end of male is round and straight. The males are small,♀ the end of ♂ male bends ♀ to venter. ♀long,about 45cm ♂ ♂ ♂short,about 3-4cm ♀ ♂ ♀ ♀ The end of the male has a spicule(交合刺) 2. 虫卵( Egg): spindle(纺锤形) tan (黄褐色) 50-54×22-23µm Egg shell is thick,and has plug(栓塞) at each end. The egg in Electronic microscope Spindle shaped with two plug-like prominence at two poles 二、生活史(life cycle) Three weeks egg (warm, wet) (develop in soil for 3 week) (develop in human body for 60 days) adult (colon) To colon (about 10 days) From mouth--- small intestine (feces) egg in infectious period juvenile worm Trichuris suis life cycle (猪毛首线虫生活史) Direct life cycle Infective stage: infective egg By ingestion 三、 致 病(Pathogenesis) The head of adults bore into intestinal mucosa, and feed on tissue fluid and blood of the host。 Mechanical damage The stimulation of secretion intestinal mucosa congestion (充血) hemorrhage(出血) engorgement(肿 胀) Note:If infection is not serious, the symptoms above don’t exist. Parasitism in the colon 四、诊断(Diagnosis ) Etiologic diagnosis: Direct Smear Fecal Flotation 五、流行( Epidemiology) Worldwide, with infections more frequent in areas with tropical weather and poor sanitation practices, especially among piglets and children. Infected pigs and persons are the important source of infection. 六、防治(Treatment and control) 1. 2. 3. 4. Periodic deworming Improve sanitation Healthy education (human) Harmless disposal of feces summary • The nematode Trichuris sp., also called the whipworm. • Geographic Distribution: Worldwide, with infections more frequent in areas with tropical weather and poor sanitation practices, and among children. • Infection occurs through accidental ingestion of eggs (which are usually found in food and water.) • Final diagnosis: Trichuriasis can be diagnosed when the eggs are detected in stool examination. • Treatment and control: Metronidazole is 90% effective in the first dose, and albendazole may also be offered as an anti-parasitic agent.