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ADLN - Perpustakaan Universitas Airlangga STUDI PENGGUNAAN OBAT PADA PASIEN GASTRITIS EROSIVA (Penelitian Dilakukan di Instalasi Rawat Inap Medik RSUD Dr. Soetomo Surabaya) RAHMA NOOR FAUZIAH dr. Titong Sugihartono, Sp.PD.,K-GEH KKB KK FF 312 11 Fau s ABSTRACT Erosive gastritis is a disease of gastric mucosal erosion due to an impaired mucosal defense. Patients with erosive gastritis require proper care to achieve optimal outcome. The purpose of the present study was to identify and analyze drug use in patients with erosive gastritis. Research was carried out prospectively from March to May 2011 at the Inpatient Wards of Dr. Soetomo Hospital of Surabaya. Data was analyzed descriptively. Of the 26 patients with erosive gastritis enrolled in this study, the major etiology were consumption of herbs (42.31%) and use of NSAIDs (30.77%). Clinical/laboratory data indicated that those patients experienced melena (84.62%), anemia (80.77%), hematemesis (50.00%), nausea (34.62%), and abdominal pain (34.62%). Drugs used in the therapy of erosive gastritis were PPI class, ARH2 class, sucralfate, and antacids. Patients received therapy in single form or in combination. The most widely used monotherapy was from PPI classes, i.e omeprazole i.v. 1-2 dd 40 mg. While the most widely used combination therapy was a combination of omeprazole i.v. 2 dd 40 mg and sucralfate p.o. i.v. 3-4 dd 15-30 mL. Intravenous route was the most frequently used initial route of therapy. The duration therapy of PPI classes is 3-21 days. Drug-related problems occurring in the study included an improper combination of omeprazole and ranitidine and potential interaction of omeprazole with clopidogrel. Keyword: Drug Utilization Study, Erosive Gastritis, Proton Pump Inhibitor, Stress Related Mucosal Disease Skripsi Studi penggunaan obat ... Rahma Noor Fauziah