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578 Clinical Snapshot Clinical Snapshot #1 Clare L. Deming, DVM North Jersey Veterinary Emergency Services Lyndhurst, New Jersey CASE PRESENTATION A 6-year-old, castrated, domestic shorthaired cat was evaluated for urethral obstruction. After the patient was stabilized and the obstruction relieved with the patient under sedation, urinalysis was conducted. 1. What is the name of this 65 × 25–µm parasite, and how did the cat become infected? 2. How significant is this finding in a cat with urethral obstruction but without crystalluria? 3. What is the recommended treatment? (See page 580 for answers and explanations.) COMPENDIUM October 2007 580 Clinical Snapshot Clinical Snapshot #1 ANSWERS & EXPLANATIONS (Case presentation on page 578) 1. Pearsonema (formerly Capillaria) plica, a trichurid parasite of cats. This parasite is acquired when a cat (definitive host) ingests an earthworm (intermediate host) infected with the first larval stages of the parasite. The first-stage larvae enter the feline host through the intestines, molt twice, then migrate through the blood to the kidneys. The larvae travel through the ureters and enter the mucosa of the bladder.1 Mature worms can reach 30 to 60 mm in length. Eggs are laid in the bladder lumen and excreted in the urine. P. plica can infect dogs, cats, foxes, wolves, and other canids.2 2. The significance is unknown. There is no evidence that Pearsonema infection contributes to feline lower urinary tract disease, and it is an uncommon finding by urinalysis. In dogs, the infection can be associated with dysuria, stranguria, and pollakiuria.3 3. One source2 recommends treatment with ivermectin at 0.2 mg/kg SC or PO, repeating the dose if necessary, or fenbendazole at 50 mg/kg PO q24h for 10 to 14 days. This remains controversial because there is no evidence that Pearsonema infection causes significant pathology in cats. Both treatments should be considered extralabel drug use, and clients should be appropriately informed. REFERENCES 1. Bowman DD: Georgi’s Parasitology for Veterinarians. Philadelphia, WB Saunders, 1999. 2. University of Pennsylvania: Pearsonema (Capillaria) plica homepage. Accessed August 2007 at cal.vet.upenn.edu/dxendopar/parasitepages/trichocephalids/c_plica.html. 3. Adams LG, Syme HM: Canine lower urinary tract diseases, in Ettinger SJ, Feldman EC (eds): Textbook of Veterinary Internal Medicine. St Louis, Elsevier, 2005, p 1872. COMPENDIUM October 2007