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Transcript
Evolution Quiz
Standard 1.2a and 1.2b
In 2007 Sarah Tishkoff studied populations of humans from all over the world trying to determine if the ability to digest
lactose was an adaptation that was selective in times of starvation. As environments changed and food was scarce, were
humans with a mutation able to turn to their livestock they herded for nutrition and did those who did not have the
mutation have a selective disadvantage?
Lactose is digested by the enzyme lactase, which is produced in the small intestine. The lactase gene codes for the enzyme
lactase. In people that are lactose intolerant, the lactase gene gets “turned off” sometime after breastfeeding stops. People
who are lactose tolerant have the lactase gene permanently “on.” Scientists have discovered that the gene remains “on”
due to mutations that are not in the lactase gene but are near it. People who are lactose tolerant are also referred as being
lactase persistent, because expression of the lactase gene persists beyond childhood. People who are lactose intolerant are
lactase nonpersistent.
Table 1: Genotype data from world regions indicating frequency of people with lactose persistence
Region
Population
No People Sampled
(n)
Number of people
with the lactose
persistence allele
Lactase Frequency
Africa
Sudan
162
73
.45
Asia
Japan
62
0
.00
Asia
China
82
8
.10
Europe
Finland
1876
1538
.82
Middle East
Saudi Arabia (Bedouin)
94
69
.73
Europe
France
58
39
.67
Indonesia
New Guinea
34
0
.00
Evolution Quiz
Answer Sheet
Name: __________________________
Period: __________
1. 1.2a: CER
Examine the data above. Make a claim to which populations were descendants of pastoral cultures
which herded livestock.
Use evidence from the table above to justify (this is the reasoning portion) your claim.
1.2b - Use the following information (and the information on the previous page) to connect evolutionary
changes in a population over time to a change in the environment.
The lactose tolerance mutation is estimated to be around 20,000 years old. However, migration from
the fertile crescent happened 8,000 years ago with crops from that region now being planted in Europe. One
hypothesis is that in shorter growing seasons of Europe, most middle-eastern plants failed, leading to
starvation. People then turned to their animals for nourishment. Complete the table below regarding lactose
digestion in adults as a selective trait in times of starvation.
Principle of Natural Selection
Variation in the population
Description based on example
Inheritance Potential
Selection on the population
Adaptation Explanation