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GENE MUTATIONS
Skeleton Outline
I.
II.
III.
What is a gene mutation?
______________________________________________________
What is a mutagen?
______________________________________________________
Point mutations
a. What is a point mutation? __________________________________________________
b. How are point mutations caused? _____________________________________________
c. What is an example of a resultant disease? ______________________________________
d. How might normal translation of DNA work?
DNA
TAC
GCA
TGG
mRNA
Amino acid
e. What would happen if a “G” substituted for an “A” on the first DNA codon?
DNA
mRNA
Amino acid
TGC
GCA
TGG
IV.
Frameshift mutations
a. What is a frameshift mutation?
_____________________________________________
b. How are frameshift mutations caused?__________________________________________
c. What is an example of a resultant disease?_______________________________________
d. What would happen if an extra “T” inserted in the first DNA codon?
DNA
TAT
CGC
ATG
G
mRNA
amino acid
V.
Types of Mutations:
a. Deletion – ______________________________________________________________
b. Insertion – ______________________________________________________________
c. Substitution – ____________________________________________________________
VI.
Are deletions and insertions considered point mutations or frameshift mutations?
______________________________________________________________
VII.
Are substitutions considered point mutations or frameshift mutations?
______________________________________________________________
VIII.
Mutating DNA can change your body’s traits and functions.
List 5 bodily changes that result from a mutation in DNA?
a. ______________________________________________________________
b. ______________________________________________________________
c. ______________________________________________________________
d. ______________________________________________________________
e. ______________________________________________________________
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