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OSTEO ARTHRITIS BY DR WAQAR OSTEOARTHRITIS It is a degenerative arthritis involving synovial joints. 1) It is the most common type of arthritis 2) More common after age 60 3) Most cases are idiopathic (primary osteoarthritis) with no know cause 4) Can occur in young ppl if there is any joint damage from before, or fracture thru a joint, or mal-alignment of bones ( secondary O.A.) PATHOGENESIS 1) There is progressive“damage & loss” of joint cartilage 2) The sub-chondral bone, which is exposed, gets sclerotic & develops cysts 3) “Osteophytes” form at the joint margins (spur like structures) 4) Cartilage damage is due to release of enzymes which destroy the collagen INFLAMMATION IN THE JOINTS IS VER MINIMAL. IT IS MAINLY A “DEGENERATIVE” JOINT DISEASE O.A. (contd.) WHICH JOINTS ARE AFFECTED? Most commonly affected are: 1) DIP joints 2) 1st carpometacarpal jt( base of the thumb) 3) Wt. bearing joints( spine, hip, knees) 4) 1st metatarso-phalangeal jt.of the foot (toe) Commonest Joints affected by : a) Gout: ? b) CPPD: ? c) OA: ? d) R.A. : ? Predisposing factors for O.A. 1) Old age 2) Obesity 3) Pre-existing joint abnormalities, fracture thru a joint, & mal-aligned bones ( occurs due to malunited fractures) 1) 2) 3) 4) 5) SIGNS/ SYMPTOMS Joint pain ( more with movement) Joint becomes stiff after resting ( gelling) Morning stiffness less than ½ hr. ( > 1 hr. in R.A) Muscle wasting around the joint Crepitus( cracking sound) during joint motion 6) Joint deformity: * Heberden’s nodes in DIP jts. * Bouchard’s nodes in PIP jts. INVESTIGATIONS 1) X-Rays: * Joint space narrowing * Subchondral bone sclerosis & cysts *Osteophytes 2) Blood tests are normal. Rheumatoid fac. neg. TREATMENT 1) Patient education 2) Guided exercises 3) Support things( stick, walker etc) 4) Analgesics( panadol, NSAIDs etc) 5) In case of a painful joint effusion, can give intra-articula steroid inj. Otherwise, no role of steroids 6) Hip /knee replacement surgery REMEMBER ALLAH HAS MADE SALAAT COMPULSORY 5 TIMES A DAY BUT HE HAS MADE “GOOD AKHLAAQ” COMPUL-SARY 24 HRS A DAY !