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Transcript
1
Diversity of neurons
STRUCTURE AND FUNCTION
by András Salma
Nervous System

Glial cells are non-neural sells that provide support
and protection for neurons In the central nervous
system, glial cells
include oligodendrocytes, astrocytes, ependymal
cells and microglia, and in the peripheral nervous
system glial cells include Schwann cells (myelin
sheat).

The purpose of neurons is to receive, process, and
transfer information in the form of chemical or
electrical signals.
2
Structural classification
(Central NS)
(Peripheral NS)
Pseudounipolar (P)
3
Pyramidic (C)
Classifcation with respect to function
Sensory neurons convey information from tissues and organs into
the central nervous system.
Motor neurons transmit signals from the central nervous system
to the effector cells. Muscular output involves peripheral nervous
system.
Interneurons are found in the brain, highly branched axons
and/or dendrites, processing signals.
4
Neurotransmitters

Cholinergic neurons: Nicotinic receptors. Acetylcholine is synthesized
from choline and acetyl coenzyme A.

GABAergic neurons: Gamma aminobutyric acid--GABA is one of two
common neuroinhibitors. GABA is synthesized from glutamate
neurotransmitters by the enzyme glutamate decarboxylase.

Glutamatergic neurons: Glutamate is one of two primary excitatory
amino acid neurotransmitter, the other being Aspartate. Glutamate
receptors are one of four categories, three of which are ligand-gated
ion channels and one of which is a G-protein coupled receptor (often
referred to as GPCR).Glutamate is synthesized from the amino acid
glutamine

Dopaminergic neurons: Dopamine is a neurotransmitter that is
connected to mood and behaviour, and modulates both pre and post
synaptic neurotransmission.

Serotonergic neurons: Serotonin can act as excitatory or inhibitory. A
lack of serotonin at postsynaptic neurons has been linked to depression.
Drugs that block the presynaptic serotonin transporter are used for
treatment, such as Prozac and Zoloft.
5