Survey
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
NPTEL – Biotechnology – Cell Biology Interesting Facts 1. Cytoskeleton is involved in cell division cycle of mitosis and meiosis which can be visualized by confocal fluorescence micrograph. 2. Cytoskeleton in orientation of cell division in contact guided cells like Single human skin fibroblasts and the skin keratinocyte. 3. Microtubule dynamics can also be altered by drugs. For example, the taxane drug used in the treatment of cancer, blocks dynamic instability by stabilizing GDP-bound tubulin in the microtubule. Nocodazole and Colchicine have the opposite effect, blocking the polymerization of tubulin into microtubules. 4. Neurodegenerative diseases like Alzheimer's disease, are associated with dysfunction of cytoskeletal components that influence vesicular biogenesis, vesicle/organelle trafficking and synaptic signaling. Questions: Q1. Do all cells possess cytoskeleton? Q2. Where are microfilaments, microtubules and intermediate filaments located in a cell? Q3. Differentiate among the structure and functions of microfilaments, microtubules and intermediate filaments. Q4. What are cytoplasmic microtrabecular system? Q5. Write about the different types of microtubules. Q6. Describe the prokaryotic cytoskeletal system. Q7. Name the different proteins that make up intermediate filaments. Joint initiative of IITs and IISc – Funded by MHRD Page 61 of 169