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CHEN 1000: Creative Technology
Exam #2
3/14/02
25 problems, 3 points each
VERSION B
1. A plant can be cloned by
(a) growing an entire plant from a clipping or single cell of another plant
(b) the polymerase chain reaction
(c) using a bacteriophage virus to create a transgenic plant
(d) introducing the DNA from an ordinary cell into a stem cell
2. Which of the following represents a legitimate concern regarding the use of bovine growth hormone?
(a) humans drinking the milk from these cows could get mad cow disease
(b) it has been found to make cows susceptible to foot and mouth disease
(c) the price of milk could drop too low because of increased production, making it difficult for
small dairy farms to stay in business
(d) bodybuilders using bovine growth hormone experience severe side effects
3. Which of the following statements regarding the insecticidal toxin from Bacillus thuringiensis
is FALSE?
(a) the gene for the toxin is inserted into transgenic plants
(b) the toxin deactivates (inhibits) an enzyme that insects use to break down plant matter
(c) it is not necessary to spray as much chemical insecticide on crops of plants that produce this
toxin
(d) the toxin is hazardous to small mammals like mice
4. A clone of a given animal is most similar to that animalÕs
(a) parent
(b) twin
(c) sibling
(d) child
5. A current biotechnology that reduces the use of chemical fertilizers involves
(a) adding insecticide genes to plants
(b) engineering bacteria to degrade toxic waste
(c) engineering plants that donÕt need nitrogen
(d) adding nitrogen-fixing helper bacteria to the soil
6. How are transgenic plants made?
(a) a plant is infected with a genetically engineered bacteriophage virus that inserts a gene into each cell
(b) rhizobial bacteria form nodules on the roots that fix nitrogen
(c) a gene is integrated into a plant cellÕs genome using a bacterium and a plant is cloned from the cell
(d) DNA is injected into an egg cell from which the nucleus has been removed
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7. Which of the following is NOT an advantage of cloning human embryos to produce stem cells?
(a) the stem cells produced are pluripotent and can develop into many different types of cells
(b) the stem cells produced will be perfectly compatible with the original cell donor
(c) this is the only way stem cells can be produced or collected
(d) genetic defects in the DNA can be corrected and the cells re-introduced into the donor
8. Some toxic waste cannot be degraded in a single step. The standard bioremediation strategy in this
case is to design a multi-step process where the toxic compound is converted into a sequence of
gradually less toxic chemicals using a series of enzymes produced in microorganisms. This process is
known as É
(a) sequential detoxification
(b) using superbugs
(c) mixed waste cleanup
(d) an enzymatic pathway
9. Which of the following is NOT a current goal of transgenic animal biotechnology?
(a) mice that are used as models of human disease
(b) pets that have better temperaments
(c) goats that produce more protein in their milk
(d) cows that produce therapeutic proteins in their milk
10. Which of the following statements regarding bioremediation is FALSE?
(a) microorganisms can be engineered to use many types of toxic waste as food
(b) enzymes produced by engineered bacteria can degrade plastics and oil
(c) bacteria cannot metabolize carcinogens because they need oxygen to survive
(d) bioremediation can be used to remove pollutants from soil and water
11. We saw a number of examples where an object or organism that is usually considered pathogenic was
used for a beneficial application. Which of the following was NOT one of the examples discussed in
class?
(a) bacteriophage viruses are used to insert DNA into bacteria
(b) a bacterium that produces crown gall tumors is used to insert genes into plant cells
(c) tumor cells are used in hybridoma technology to produce monoclonal antibodies
(d) toxic PCB chemicals can be used as vaccines against cancer
12. Which of the following statements is FALSE?
(a) all major religious groups are against embryonic cloning for the production of stem cells
(b) Prince Charles of England is against genetically-modified organisms on religious grounds
(c) the Catholic Church is against therapeutic cloning because it involves the destruction of an
embryo which it views as a living human entity
(d) President Bush supports a total ban on human embryonic cloning
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13. Which of the following is NOT true of the risk assessment method of evaluating a
technology?
(a) a technology should be banned on the basis of any evidence of risk or possible danger
(b) the familiarity of a technology affects the perceived risks and benefits
(c) the risks and benefits of a technology must be weighed against each other
(d) a beneficial technology should not be pursued if the risks are too great
14. Which of the following is NOT made from a composite material?
(a) a plastic bag
(b) bone
(c) concrete
(d) an oyster shell
15. Which of the following properties is most difficult to achieve in a plastic?
(a) flexibility
(b) light weight
(c) scratch-resistance
(d) corrosion-resistance
16. Which of the following statements is NOT a reason that liposomes are used to treat cancer?
(a)
(b)
(c)
(d)
The oil inside a liposome can dissolve tumors.
Stealth liposomes can be prepared that are not quickly attacked by the immune system.
Liposomes can be targeted to stick preferentially on tumor cells.
Incorporating powerful chemotherapy drugs inside liposomes can reduce side effects
17. A material that is made by stacking thin layers of material is called a
(a) plastic
(b) laminate
(c) ceramic
(d) protein
18. Imagine you have a material that is very strong and tough, but not corrosion-resistant. What type of
biomimetic strategy would be the best way to add corrosion-resistance?
(a) use the material as part of a composite
(b) make a laminate using the material
(c) add a corrosion-resistant coating to the material
(d) make tiny particles out of the material
19. Which of the following is NOT considered a physical property of a material?
(a) corrosion-resistance
(b) flexibility
(c) strength
(d) desirability
20. Which of the following statements is NOT true?
(a)
(b)
(c)
(d)
Hydrogen bonds are stronger than covalent (chemical) bonds
The hydrophobic effect describes one way molecules can interact with each other.
Water has unusual properties because of its extensive hydrogen-bonding network.
A molecule is a group of atoms held together by covalent bonds.
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21. Which of the following amphiphilic molecules would you choose if you wanted reverse micelles to
self-assemble?
(a)
(b)
(c)
(d)
22. Which of the following statements explains why this picture is wrong?
(a) wedge-shaped amphiphilic molecules generally form bilayers.
(b) strands of DNA hybridize only if they are complementary
(c) hydrophobic tails of amphiphilic molecules should not be in contact with water.
(d) negatively charged molecules would repel each other
water
23. Which of the following assemblies would be useful templates for making polymer nanoparticles if the
monomers were soluble in oil but not in water?
(a) swollen reverse micelles
(b) liposomes
(c) swollen micelles
(d) a DNA double helix
24. Which of the following is NOT one of the reasons nanoparticles are valuable?
(a) incorporating nanoparticles into composite materials can add strength and hardness
(b) nanoparticles of some materials are fluorescent and can be used to label biomolecules
(c) reactive nanoparticles can be used to destroy some hazardous substances
(d) nanoparticles can be prepared easily by breaking up larger particles
25. A 1 gram piece of gold is divided into a powder of nanoparticles that are 10 nm in diameter. The
total surface area of all the nanoparticles in the powder is 100 square meters. If the same amount of
gold (1 gram) is divided into a powder of nanoparticles that are 20 nm in diameter, what will be the
approximate total surface area of all the nanoparticles in the powder?
(a) less than 100 square meters
(b) exactly 100 square meters
(c) greater than 100 square meters
(d) cannot say without more information
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CHEN 1000: Creative Technology
Exam #2 – Extra Credit
3/14/02
PRINT NAME:
CU ID#:
SCORE:
/6
We have talked quite a bit in this course about using biomimetic strategies to create novel materials and
devices. These strategies have certain advantages but also some limitations. Please choose one
advantage and one limitation and describe them briefly below.
Important note: I am not asking you to give examples of a biomimetic application or technology, but to
give a reason why the strategy is beneficial and a way in which the strategy is limited.
Advantage (3 points):
Limitation (3 points):
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ANSWERS
1. a
2. c
3. d
4. b
5. d
6. c
7. c
8. d
9. b
10. c
11. d
12. a
13. a
14. a
15. c
16. a
17. b
18. c
19. d
20. a
21. b
22. c
23. c
24. d
25. a
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