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ROUTES OF MEDICATION ADMINISTRATION
Route
Indications
Time of Onset
(Action)
Oral
Safest and least invasive method of
administration.
Requires an intact Gag reflex
30 - 60 minutes
Sublingual
Used when rapid effect is required
Avoid diluting the dosage by not drinking
for 30-minutes after administration
Several minutes
Buccal
Limited number of medications available
for use of this route
Convenient. Can cause local irritation to
buccal lining as tablet/lozenge retained in
cheek for up to one-hour
Several minutes
Transdermal
Convenient dosage form.
Provides continuous systemic absorption
over extended time (hours, days)
30 – 60 minutes
Rectal
Useful when patient unable to tolerate
oral medication and parenteral route is
not indicated.
Good absorption and avoids first pass
metabolism.
15 – 30 minutes
Examples
(Provide Two for each)
Route
Indications
Time of Onset
(Action)
Vaginal
For local effect
15 – 30 minutes
Topical
For local effects on the skin and mucous
membrane of the eye, ear, nose and
mouth
Within one hour
Inhalation
Used for local effect within the respiratory Within one
tract
minute
Subcutaneous
Used for drugs that may be inactivated by Within several
the gastrointestinal tract
minutes
Intramuscular
Used for drugs that have poor oral
absorption, when a faster rate of action is Within several
required than other routes.
minutes
Blood concentrations achieved quickly.
Intravenous
Used in emergency situations for
immediate effect. Also used where large
volumes of a medication are required to
be administered (ie. Infusion)
Within one
minute
Examples
(Provide Two for each)