The Straight Facts About Human Growth Hormone (hGH)
... or effect. These anti-somatostatin treatments have been intellectually honest but of disappointing effect; typically showing a 1% or so rise in IGF-1 levels, and no measurable clinical difference in patient outcomes. There is no current recommendation favoring the use of these compounds. What's the ...
... or effect. These anti-somatostatin treatments have been intellectually honest but of disappointing effect; typically showing a 1% or so rise in IGF-1 levels, and no measurable clinical difference in patient outcomes. There is no current recommendation favoring the use of these compounds. What's the ...
Cover Story - Medical Laboratory Observer
... shaped like a butterfly, divided into two lobes connected by the isthmus, and is located in the lower anterior neck. The two lobes are situated on either sides of the trachea. Measurements of thyrotropin (TSH) and free thyroxine (FT4) are the most useful tests for assessing thyroid function. Other te ...
... shaped like a butterfly, divided into two lobes connected by the isthmus, and is located in the lower anterior neck. The two lobes are situated on either sides of the trachea. Measurements of thyrotropin (TSH) and free thyroxine (FT4) are the most useful tests for assessing thyroid function. Other te ...
ACTH, -MSH, and control of cortisol release: cloning, sequencing
... the melanocortin-2 and melanocortin-5 receptor (MC2R and MC5R). So far, no functional melanocortin receptor (MCR) profile of fish head kidney has been presented, and such a profile would definitively establish the cortisol-producing cell as target for ACTH and ␣-MSH. We believe that the study of MCR ...
... the melanocortin-2 and melanocortin-5 receptor (MC2R and MC5R). So far, no functional melanocortin receptor (MCR) profile of fish head kidney has been presented, and such a profile would definitively establish the cortisol-producing cell as target for ACTH and ␣-MSH. We believe that the study of MCR ...
LHRH Agonists Antagonists
... LHRH Agonists and Antagonists LHRH, also known as GnRH (gonadotropin-releasing hormone) or gonadorelin, is an important hypothalamic hormone which regulates reproductive functions and the development and maintenance of secondary sex characteristics in males and females. It acts directly on the pitu ...
... LHRH Agonists and Antagonists LHRH, also known as GnRH (gonadotropin-releasing hormone) or gonadorelin, is an important hypothalamic hormone which regulates reproductive functions and the development and maintenance of secondary sex characteristics in males and females. It acts directly on the pitu ...
Thyroid Function in Dogs - Diagnostic Center for Population and
... autoantibody result. What does this mean? This most likely reflects the presence of subclinical thyroiditis (but very rarely might indicate thyroid neoplasia in an older dog). In these cases, there is evidence of pathology within the thyroid glands, but not to the extent that it is interfering with ...
... autoantibody result. What does this mean? This most likely reflects the presence of subclinical thyroiditis (but very rarely might indicate thyroid neoplasia in an older dog). In these cases, there is evidence of pathology within the thyroid glands, but not to the extent that it is interfering with ...
Interpretation of thyroid function tests
... thyroid function test results are grouped into six different patterns. We propose that if assays for thyrotropin, free T3, and free T4 are all done, knowledge of these patterns coupled with clinical details and simple additional tests allow a diagnosis to be made in almost all cases. There have been ...
... thyroid function test results are grouped into six different patterns. We propose that if assays for thyrotropin, free T3, and free T4 are all done, knowledge of these patterns coupled with clinical details and simple additional tests allow a diagnosis to be made in almost all cases. There have been ...
Peak cortisol response to corticotropin
... disease [7, 8]. Although frequently used, the low-dose ACTH stimulation test does not allow for direct measurement of pituitary response, and concerns have been raised about the difficulty of reliably diluting the low dose of medication with precision [9]. The standard-dose ACTH stimulation test may ...
... disease [7, 8]. Although frequently used, the low-dose ACTH stimulation test does not allow for direct measurement of pituitary response, and concerns have been raised about the difficulty of reliably diluting the low dose of medication with precision [9]. The standard-dose ACTH stimulation test may ...
essential thyroid function biomarkers
... Thyroid disease or dysfunction can explain a wide variety of symptoms (see list on page 3), yet it is notoriously under-diagnosed. The Colorado Thyroid Disease Prevalence Study published in 20001 found that 9.9% of the study population consisted of people who were not being treated for thyroid probl ...
... Thyroid disease or dysfunction can explain a wide variety of symptoms (see list on page 3), yet it is notoriously under-diagnosed. The Colorado Thyroid Disease Prevalence Study published in 20001 found that 9.9% of the study population consisted of people who were not being treated for thyroid probl ...
28 Endocrinology of Complex Life Cycles: Amphibians
... threshold of minimum body size that must be reached before metamorphosis is possible and that larval growth rates determine the timing of metamorphosis after this minimum size has been attained. Werner (1986) added mortality risk in the larval and adult habitats to the list of factors that ultimatel ...
... threshold of minimum body size that must be reached before metamorphosis is possible and that larval growth rates determine the timing of metamorphosis after this minimum size has been attained. Werner (1986) added mortality risk in the larval and adult habitats to the list of factors that ultimatel ...
Mechanisms of thyroid hormone action
... isoforms (2, 14, 15). The selective actions of thyroid hormone receptors are influenced by local ligand availability (1, 16); by transport of thyroid hormone into the cell by monocarboxylate transporter 8 (MCT8) or other related transporters (17); by the relative expression and distribution of the T ...
... isoforms (2, 14, 15). The selective actions of thyroid hormone receptors are influenced by local ligand availability (1, 16); by transport of thyroid hormone into the cell by monocarboxylate transporter 8 (MCT8) or other related transporters (17); by the relative expression and distribution of the T ...
Effect of thyroid stimulating hormone on the ultra
... axolotl. According to Kühn et al., (2005) there is entanglement of functions between TH and C in an induced metamorphosis of the neotenic axolotl. On the other hand, the enigma of neoteny in the axolotl cannot be attributed to a deficient interrenal axis since a normal in vitro regulation of interre ...
... axolotl. According to Kühn et al., (2005) there is entanglement of functions between TH and C in an induced metamorphosis of the neotenic axolotl. On the other hand, the enigma of neoteny in the axolotl cannot be attributed to a deficient interrenal axis since a normal in vitro regulation of interre ...
the effect of human growth hormone in hypopituitary dwarfism
... attain full skeletal maturity and a final height of injected HGH about 20-30 minutes. Parker et al. around 150 cm. This is more than in an untreated (1962) estimated the normal daily secretion rate in an patient but is still not normal. These steroids have a adult to be around 5 mg. or 3 mg./m.2. Si ...
... attain full skeletal maturity and a final height of injected HGH about 20-30 minutes. Parker et al. around 150 cm. This is more than in an untreated (1962) estimated the normal daily secretion rate in an patient but is still not normal. These steroids have a adult to be around 5 mg. or 3 mg./m.2. Si ...
the effect of human growth hormone in hypopituitary dwarfism
... attain full skeletal maturity and a final height of injected HGH about 20-30 minutes. Parker et al. around 150 cm. This is more than in an untreated (1962) estimated the normal daily secretion rate in an patient but is still not normal. These steroids have a adult to be around 5 mg. or 3 mg./m.2. Si ...
... attain full skeletal maturity and a final height of injected HGH about 20-30 minutes. Parker et al. around 150 cm. This is more than in an untreated (1962) estimated the normal daily secretion rate in an patient but is still not normal. These steroids have a adult to be around 5 mg. or 3 mg./m.2. Si ...
STRUCTURE AND FUNCTION OF THE THYROID GLAND
... ! Apply knowledge acquired from mastery of basic learning objectives concerning thyroid function, physiology and pathology. ! Understand the many and varied manifestations of thyroid disease in key sub-populations. Drug therapy options are limited, but abnormal thyroid function is prevalent in diffe ...
... ! Apply knowledge acquired from mastery of basic learning objectives concerning thyroid function, physiology and pathology. ! Understand the many and varied manifestations of thyroid disease in key sub-populations. Drug therapy options are limited, but abnormal thyroid function is prevalent in diffe ...
Curriculum Vitae Joel Tabak-Sznajder
... Tabak, J., Gonzelez-Iglesias, A. E., Cristancho-Gordo, R., & Bertram, R. (presented 2012). Multiple actions of hypothalamic oxytocin on pituitary cells. Poster presentation at Annual meeting, Society for Neuroscience, New Orleans, LA. (International) Velez, P., Helena, C. V., Stathopoulos, A. M., Fl ...
... Tabak, J., Gonzelez-Iglesias, A. E., Cristancho-Gordo, R., & Bertram, R. (presented 2012). Multiple actions of hypothalamic oxytocin on pituitary cells. Poster presentation at Annual meeting, Society for Neuroscience, New Orleans, LA. (International) Velez, P., Helena, C. V., Stathopoulos, A. M., Fl ...
1. Dynamic Function Tests in Endocrinology
... • Serum TSH (2nd or 3rd generation) as first line. This strategy may be cost-effective for a wide range of clinical purposes but is not the best as it may be insufficient in situations where the pituitary-thyroid axis is disturbed such as, secondary hypothyroidism (hypopituitarism), during optimizat ...
... • Serum TSH (2nd or 3rd generation) as first line. This strategy may be cost-effective for a wide range of clinical purposes but is not the best as it may be insufficient in situations where the pituitary-thyroid axis is disturbed such as, secondary hypothyroidism (hypopituitarism), during optimizat ...
Clinical Approach to Thyroid Disease
... and any neck swelling. Erythema overlying a tender swelling may be due to suppurative thyroiditis or infected thyroglossal cyst or brachial cleft cyst.3 Slightly extend the neck and inspect the area from the thyroid cartilage to the sternal notch and also instruct the patient to do a swallowing act. ...
... and any neck swelling. Erythema overlying a tender swelling may be due to suppurative thyroiditis or infected thyroglossal cyst or brachial cleft cyst.3 Slightly extend the neck and inspect the area from the thyroid cartilage to the sternal notch and also instruct the patient to do a swallowing act. ...
Evolution of the role of GnRH in animal (Metazoan) biology
... variants and analogs are active in stimulating some aspect of reproduction. In C. intestinalis, mammalian GnRH and cGnRH-I, tested in in vitro incubations of gonads, were shown to induce the release of sex steroids (Di Fiore et al., 2000). Injections of various GnRH forms, including the testing of t ...
... variants and analogs are active in stimulating some aspect of reproduction. In C. intestinalis, mammalian GnRH and cGnRH-I, tested in in vitro incubations of gonads, were shown to induce the release of sex steroids (Di Fiore et al., 2000). Injections of various GnRH forms, including the testing of t ...
2,4,6-Tribromophenol Interferes with the Thyroid Hormone System
... To investigate the effects of TBP in the mouse pituitary gland, we observed several genes related to thyroid hormones. Mice were exposed to TBP with or without thyroid hormones to investigate the competitive effects of TBP with blood transthyretin. The levels of a down-regulated indicator of thyroid ...
... To investigate the effects of TBP in the mouse pituitary gland, we observed several genes related to thyroid hormones. Mice were exposed to TBP with or without thyroid hormones to investigate the competitive effects of TBP with blood transthyretin. The levels of a down-regulated indicator of thyroid ...
Polychlorinated Biphenyls as Disruptors of Thyroid Hormone Action
... that are correlated with background exposure to PCBs (Dussault and Walker, 1983; Porterfield, 1994). If PCBs affect brain development by interfering with thyroid hormone action, then PCBs should exert effects on developmental processes known to be responsive to thyroid hormone in experimental animal ...
... that are correlated with background exposure to PCBs (Dussault and Walker, 1983; Porterfield, 1994). If PCBs affect brain development by interfering with thyroid hormone action, then PCBs should exert effects on developmental processes known to be responsive to thyroid hormone in experimental animal ...
Biology strony.indd
... nutrients in many animal species causes disturbances in the secretion of gonadotropic hormones in immature as well as in adult mammals [1, 6, 11]. The decreased hypothalamic pulsatile secretion of the gonadotropic hormone-releasing hormone (GnRH), resulting in decreased luteinizing hormone (LH) synt ...
... nutrients in many animal species causes disturbances in the secretion of gonadotropic hormones in immature as well as in adult mammals [1, 6, 11]. The decreased hypothalamic pulsatile secretion of the gonadotropic hormone-releasing hormone (GnRH), resulting in decreased luteinizing hormone (LH) synt ...
Thyroid-Stimulating Hormone: Neuroregulation and Clinical
... obtained with regard to the role of serotonin. Grimm & Reichlin (1973) found that the serotonin precursor 5-hydroxytryptophan inhibited the release of thyrotrophin-releasing hormone (TRH) radioactivity from mouse hypothalamic slices and suggested that serotonin was an inhibitory neurotransmitter in ...
... obtained with regard to the role of serotonin. Grimm & Reichlin (1973) found that the serotonin precursor 5-hydroxytryptophan inhibited the release of thyrotrophin-releasing hormone (TRH) radioactivity from mouse hypothalamic slices and suggested that serotonin was an inhibitory neurotransmitter in ...
Growth Hormone–Releasing Hormone in HIV
... a more physiologic pattern of GH than that achieved with pharmacologic GH therapy. With GHRH, feedback inhibition of insulin-like growth factor 1 (IGF-1) (a hepatic factor the secretion of which is stimulated by GH and which is responsible for many of its actions) may help to prevent excessive GH se ...
... a more physiologic pattern of GH than that achieved with pharmacologic GH therapy. With GHRH, feedback inhibition of insulin-like growth factor 1 (IGF-1) (a hepatic factor the secretion of which is stimulated by GH and which is responsible for many of its actions) may help to prevent excessive GH se ...
laboratory tests of thyroid function: pitfalls in interpretation
... Thus, while clinicians may be alert to the possibility of thyroid dysfunction, they may not be familiar with the interpretation of laboratory tests, or with the various factors that can compromise the laboratory tests. Good communication between the requesting clinician and the laboratory is therefo ...
... Thus, while clinicians may be alert to the possibility of thyroid dysfunction, they may not be familiar with the interpretation of laboratory tests, or with the various factors that can compromise the laboratory tests. Good communication between the requesting clinician and the laboratory is therefo ...
Chapter 7 The Thyroid Gland Introduction - Rose
... Synthesis and release of TBG are affected by several hormones: glucocorticoids and androgens reduce the amount of TBG, while estrogens increase TBG levels, especially during pregnancy. These observations are of some clinical relevance for individuals being treated with thyroid hormone, since the lev ...
... Synthesis and release of TBG are affected by several hormones: glucocorticoids and androgens reduce the amount of TBG, while estrogens increase TBG levels, especially during pregnancy. These observations are of some clinical relevance for individuals being treated with thyroid hormone, since the lev ...
Hypopituitarism
Hypopituitarism is the decreased (hypo) secretion of one or more of the eight hormones normally produced by the pituitary gland at the base of the brain. If there is decreased secretion of most pituitary hormones, the term panhypopituitarism (pan meaning ""all"") is used.The signs and symptoms of hypopituitarism vary, depending on which hormones are undersecreted and on the underlying cause of the abnormality. The diagnosis of hypopituitarism is made by blood tests, but often specific scans and other investigations are needed to find the underlying cause, such as tumors of the pituitary, and the ideal treatment. Most hormones controlled by the secretions of the pituitary can be replaced by tablets or injections. Hypopituitarism is a rare disease, but may be significantly underdiagnosed in people with previous traumatic brain injury. The first description of the condition was made in 1914 by the German physician Dr Morris Simmonds.