Administration of resveratrol: What formulation
... However, therapeutic application of these beneficial effects of resveratrol remains very limited due to its short biological half-life, labile properties, and rapid metabolism and elimination [10]. Results from pharmacokinetic studies indicate that the oral bioavailability of resveratrol is almost ze ...
... However, therapeutic application of these beneficial effects of resveratrol remains very limited due to its short biological half-life, labile properties, and rapid metabolism and elimination [10]. Results from pharmacokinetic studies indicate that the oral bioavailability of resveratrol is almost ze ...
BIOAVAILABILITY ENHANCEMENT TECHNIQUES OF HERBAL MEDICINE: A CASE EXAMPLE OF CURCUMIN
... of human diseases especially for cancer therapeutics. It was proved to be safe even used at very high dose. However, due to its very low bioavailability, curcumin has not yet been approved as a therapeutic agent. Many attempts have been made to increase curcumin bioavailability via the increase of i ...
... of human diseases especially for cancer therapeutics. It was proved to be safe even used at very high dose. However, due to its very low bioavailability, curcumin has not yet been approved as a therapeutic agent. Many attempts have been made to increase curcumin bioavailability via the increase of i ...
PHARMACEUTICAL AND PHARMACOLOGICAL PROFILE OF GUAR GUM AN OVERVIEW Review Article
... oscillatory rheology and differential scanning calorimetry.[3]. ...
... oscillatory rheology and differential scanning calorimetry.[3]. ...
Supramolecularly engineered phospholipids
... acetonide reacted with an excess of chlorooxodioxaphospholane in tetrahydrofuran (THF) at 0 C to yield uridineoxo-dioxaphospholane phosphate. This phosphate was transferred to a pressure tube and heated for 24 h with TEA in acetonitrile to give UPC. UPE was synthesized using two different procedure ...
... acetonide reacted with an excess of chlorooxodioxaphospholane in tetrahydrofuran (THF) at 0 C to yield uridineoxo-dioxaphospholane phosphate. This phosphate was transferred to a pressure tube and heated for 24 h with TEA in acetonitrile to give UPC. UPE was synthesized using two different procedure ...
Manuscript_12122012_revised
... molecular weight heparin bioavailability following oral gavage in rats (Yang et al., 2005), while studies in mice also showed increased oral delivery of a leptin analogue (Lee et al., 2010) and octreotide (Maggio and Grasso, 2011). Recent mechanistic evaluation of TDM as an intestinal permeation enh ...
... molecular weight heparin bioavailability following oral gavage in rats (Yang et al., 2005), while studies in mice also showed increased oral delivery of a leptin analogue (Lee et al., 2010) and octreotide (Maggio and Grasso, 2011). Recent mechanistic evaluation of TDM as an intestinal permeation enh ...
Sol-gel technology for biomedical engineering
... and a Vicker’s hardness tester, the thermal properties were studied using differential scanning calorimetry and dilatometry, and the crystallization of the bioglass was examined by meand of X-ray diffraction and scanning electron microscopy. The sintered bioglass discs were then immersed in the simu ...
... and a Vicker’s hardness tester, the thermal properties were studied using differential scanning calorimetry and dilatometry, and the crystallization of the bioglass was examined by meand of X-ray diffraction and scanning electron microscopy. The sintered bioglass discs were then immersed in the simu ...
Acknowledgement - ResearchSpace@Auckland
... and humans. Naltrexone can be considered as a new therapeutic agent for treatment of diabetic keratopathy. To our best knowledge, an ophthalmic formulation has not yet been developed for naltrexone hydrochloride (NTX) nor has it been properly formulated in a liquid dosage form. Niosomes are non-ioni ...
... and humans. Naltrexone can be considered as a new therapeutic agent for treatment of diabetic keratopathy. To our best knowledge, an ophthalmic formulation has not yet been developed for naltrexone hydrochloride (NTX) nor has it been properly formulated in a liquid dosage form. Niosomes are non-ioni ...
biodegradable implants with different drug release - diss.fu
... Some parenteral controlled-release drug products have been approved and launched onto the global pharmaceutical market during the last decade (Table 1). The new drug products tend to overcome the problems of conventional systems and exhibit the benefits of parenteral controlled-release drug delivery ...
... Some parenteral controlled-release drug products have been approved and launched onto the global pharmaceutical market during the last decade (Table 1). The new drug products tend to overcome the problems of conventional systems and exhibit the benefits of parenteral controlled-release drug delivery ...
pH-Sensitive Core-Shell Nanoparticles for Intracellular Drug Delivery
... William M. Deen Carbon P. Dubbs Professor of Chemical Engineering Chairman, Committee for Graduate Students ...
... William M. Deen Carbon P. Dubbs Professor of Chemical Engineering Chairman, Committee for Graduate Students ...
CHEWING GUM - International Journal of Pharmaceutical Sciences
... acid. Another commercially available medicated chewing gum is dimenhydrinate – containing chewing gum for motion sickness. However, chewing gum did not gain acceptance as a reliable drug delivery system until 1978, when nicotine chewing gum became available3, 4. Chewing gum ...
... acid. Another commercially available medicated chewing gum is dimenhydrinate – containing chewing gum for motion sickness. However, chewing gum did not gain acceptance as a reliable drug delivery system until 1978, when nicotine chewing gum became available3, 4. Chewing gum ...
Review Biomedical applications of collagen
... fibers with extra strength and stability through its self-aggregation and cross-linking. In most of drug delivery systems made of collagen, in vivo absorption of collagen is controlled by the use of crosslinking agents, such as glutaraldehyde (Barbani et al., 1995), chromium tanning (Bradley and Wil ...
... fibers with extra strength and stability through its self-aggregation and cross-linking. In most of drug delivery systems made of collagen, in vivo absorption of collagen is controlled by the use of crosslinking agents, such as glutaraldehyde (Barbani et al., 1995), chromium tanning (Bradley and Wil ...
Titanium oxide antibacterial surfaces in biomedical devices
... Department of Chemistry, Materials, and Chemical Engineering “Giulio Natta”, Politecnico di Milano, Milan - Italy ...
... Department of Chemistry, Materials, and Chemical Engineering “Giulio Natta”, Politecnico di Milano, Milan - Italy ...
Bahauddin Zakariya University Multan Pakistan.
... “Formulation Development of Ranitidine Hydrochloride containing wafers and its invitro kinetic studies” is based on the result of research study conducted by candidate under my supervision. No portion of this thesis work has formerly been offered for higher degree in this university or any other ins ...
... “Formulation Development of Ranitidine Hydrochloride containing wafers and its invitro kinetic studies” is based on the result of research study conducted by candidate under my supervision. No portion of this thesis work has formerly been offered for higher degree in this university or any other ins ...
ORGANIC SOLVENTS IN THE PHARMACEUTICAL INDUSTRY
... for control of residual solvent amounts, but sometimes the presence of RS at levels well within acceptable limits, could entail the risk of inducing phase transformations and jeopardizing the physicochemical stability of an active substance, and finally the quality of the dosage form. A few reports ...
... for control of residual solvent amounts, but sometimes the presence of RS at levels well within acceptable limits, could entail the risk of inducing phase transformations and jeopardizing the physicochemical stability of an active substance, and finally the quality of the dosage form. A few reports ...
Aggarwal Shweta et al. IRJP 2013, 4 (2) INTERNATIONAL
... and a number of chains are interconnected by the formation of new inter chain linkages. A three dimensional network is then formed. If the degree of reticulation is sufficiently high, the matrix of the polymers becomes insoluble in water (but swellable in water) and in organic solvents7. i) Classifi ...
... and a number of chains are interconnected by the formation of new inter chain linkages. A three dimensional network is then formed. If the degree of reticulation is sufficiently high, the matrix of the polymers becomes insoluble in water (but swellable in water) and in organic solvents7. i) Classifi ...
Medicated Chewing Gum- A Mobile Oral Drug Delivery System
... International Journal of PharmTech Research CODEN (USA): IJPRIF ISSN : 0974-4304 Vol.6, No.1, pp 35-48, Jan-March 2014 ...
... International Journal of PharmTech Research CODEN (USA): IJPRIF ISSN : 0974-4304 Vol.6, No.1, pp 35-48, Jan-March 2014 ...
THE AMERICAN UNIVERSITY IN CAIRO School of Sciences and Engineering
... biorelevent media: fast gastric (FaSSGF), fast intestinal (FaSSIF) and fed intestinal media (FeSSIF). The curcumin release in gastric media was negligible and this was attributed to its low solubility in these media and to the shrinkage of alginate beads in the acidic pH environment. Curcumin releas ...
... biorelevent media: fast gastric (FaSSGF), fast intestinal (FaSSIF) and fed intestinal media (FeSSIF). The curcumin release in gastric media was negligible and this was attributed to its low solubility in these media and to the shrinkage of alginate beads in the acidic pH environment. Curcumin releas ...
HIGH INITIAL BURST RELEASE OF GENTAMICIN FORMULATED AS PLGA MICROSPHERES
... Antibiotic treatment of orthopaedic infection is complicated by systemic toxicity and the need of effective therapeutic concentration necessary to ensure optimum killing of bacteria. To overcome the problem of systemic toxicity and to achieve a high initial release followed by sustained release of a ...
... Antibiotic treatment of orthopaedic infection is complicated by systemic toxicity and the need of effective therapeutic concentration necessary to ensure optimum killing of bacteria. To overcome the problem of systemic toxicity and to achieve a high initial release followed by sustained release of a ...
2 AgCHNES JUN Engineered Microneedles for Transcutaneous Vaccine Delivery
... correlated with a similarly potent systemic and mucosal humoral response, together suggesting the utility of this approach for non-invasive adenoviral immunization in a model close to humans. Together these results strongly demonstrate the potential of materials engineering strategies for the effect ...
... correlated with a similarly potent systemic and mucosal humoral response, together suggesting the utility of this approach for non-invasive adenoviral immunization in a model close to humans. Together these results strongly demonstrate the potential of materials engineering strategies for the effect ...
COMSOL Announces Chemical Reaction Engineering Module
... Jamieson. The module, which solves problems that couple structural mechanics, microfluidics, and electromagnetics, extends the core capabilities of the COMSOL Multiphysics modeling and simulation environment for the unique engineering problems encountered in the design and modeling of microscale ele ...
... Jamieson. The module, which solves problems that couple structural mechanics, microfluidics, and electromagnetics, extends the core capabilities of the COMSOL Multiphysics modeling and simulation environment for the unique engineering problems encountered in the design and modeling of microscale ele ...
The Potential of Stimuli-Responsive Nanogels in Drug and Active
... poly(N-vinylcaprolactam) (PVCL), is considered adequate for delivery systems and to be used in biomedical devices, due to its biocompatibility and VPPT in the physiological temperature region (32–38 ◦ C). This allows PVCL to be considered as an adequate material for the design of biomedical devices ...
... poly(N-vinylcaprolactam) (PVCL), is considered adequate for delivery systems and to be used in biomedical devices, due to its biocompatibility and VPPT in the physiological temperature region (32–38 ◦ C). This allows PVCL to be considered as an adequate material for the design of biomedical devices ...
Comparison of HFNC, Bubble CPAP, and SiPAP on Aerosol
... Arzu Ari, PhD, RRT, PT, CPFT, FAARC Committee Chair ...
... Arzu Ari, PhD, RRT, PT, CPFT, FAARC Committee Chair ...
- International Journal of Pharmaceutical Sciences and
... included to provide whiteness to the final product. Glidants: Improve the flow property of material from hopper to the die cavity by reducing interparticulate friction. Colloidal silica, that is, syloid, pyrogenic silica (0.25%), hydrated sodium silicoaluminate (0.75%) and corn starch (3 -- 10%) are ...
... included to provide whiteness to the final product. Glidants: Improve the flow property of material from hopper to the die cavity by reducing interparticulate friction. Colloidal silica, that is, syloid, pyrogenic silica (0.25%), hydrated sodium silicoaluminate (0.75%) and corn starch (3 -- 10%) are ...
Potential applications of chitosan in veterinary medicine
... skin grafting template, hemostatic agent and drug delivery vehicle. In this section, various investigations carried out recently on veterinary applications of chitosan are discussed as well as their potential uses in veterinary medicine. ...
... skin grafting template, hemostatic agent and drug delivery vehicle. In this section, various investigations carried out recently on veterinary applications of chitosan are discussed as well as their potential uses in veterinary medicine. ...
CASSIA ALATA Research Article MULHAM ALFATAMA, KAUSAR AHMAD, FARAHIDAH MOHAMED
... Microencapsulation by solvent evaporation method has been widely employed in pharmaceutical industries1. Application of microencapsulated drug delivery systems for medical and pharmaceutical uses have also been widely explored and some successfully used clinically. The micro-carrier systems have cli ...
... Microencapsulation by solvent evaporation method has been widely employed in pharmaceutical industries1. Application of microencapsulated drug delivery systems for medical and pharmaceutical uses have also been widely explored and some successfully used clinically. The micro-carrier systems have cli ...
Nicholas A. Peppas
Nicholas (Nikolaos) A. Peppas (Greek: Νικόλαος Α. Πέππας; born in Athens, Greece on August 25, 1948) is a chemical and biomedical engineer whose leadership in biomaterials science and engineering, drug delivery, bionanotechnology, pharmaceutical sciences, chemical and polymer engineering has led to numerous biomedical products or devices.